Steve Mount

BSCI410, Molecular Genetics
CBMG688I, Advanced Genetics (graduate core course)

Research in the Mount lab is devoted to understanding how multicellular organisms accomplish the correct processing of RNA from protein-coding genes. This involves identifying the elements of primary sequence information that determine where (and whether or not) splicing will occur, determining which components of the splicing machinery play especially salient roles in recognizing those signals, and determining how those factors act.

Zhang and Mount 2009. Two alternatively spliced isoforms of the Arabidopsis SR45 protein have distinct roles during normal plant development. Plant Physiol. 150:1450-1458.

Ming et al. 2008. The draft genome of the transgenic tropical fruit tree papaya (Carica papaya Linnaeus). Nature 452:991-6.

Clark et al. 2007. Evolution of genes and genomes on the Drosophila phylogeny. Nature 450:203-218.

Dogan et al. 2007. Features generated for computational splice-site prediction correspond to functional elements.BMC Bioinformatics 8:410

Dogan et al. 2007. SplicePort--an interactive splice-site analysis tool. Nucleic Acids Res.35(Web Server issue):W285-91

Mount et al. 2007. Spliceosomal small nuclear RNA genes in 11 insect genomes.RNA 13:5-14

Pertea et al. 2007. A computational survey of candidate exonic splicing enhancer motifs in the model plant Arabidopsis thaliana. BMC Bioinformatics 8:159

B.A., Rice University, 1978
Ph.D., Yale University, 1983.